One of the major tools to evaluate this type of pathology is the neuroendocrine neuroendocrine cancer aggressive as chromogranin A, serotonin, urinary 5-hydroxy indolacetic acid, and neuron specific enolase.
They change related to the disease progression, regardless therapy. Some of the drugs that are used for NETs as somatostatin analogs for example octreotide might interfere with glucose metabolism.
We analyzed in a retrospective study of 2 years the dynamic of the NET markers and the glycemia profile.
Endocrine cancer review
Material and Methods. All the patients had at least one assay per year. The dose of neuroendocrine cancer aggressive varied from 20 to 50 mg, monthly. The fasting glucose insignificantly changed from baseline after 2 years. No new case of diabetes was registered. One case of known diabetes needed insulin but interferon therapy was also added during this time period.
Understanding your Neuroendocrine Cancer Diagnosis
The chromogranin A had sustained high values for all the 9 cases, marking the disease progression. The neuron specific enolase significantly increased, and the serum serotonin as well as neuroendocrine cancer aggressive 5HIIA was much higher in 2 cases with aggressive carcinoid symptoms.
The NET markers and the glucose metabolism are most useful tools in the management of NETs, yet they are not correlated. Neuroendocrine tumors.
Endocr Relat Cancer. DOI: Oberndorfer S. Karzinoide tumoren des dunndarms.
Aggressive variants of prostate cancer - Are we ready to apply specific treatment right neuroendocrine cancer aggressive Cancer Treat Rev. In most cases, prostate cancer essentially depends on androgen receptor signaling axis, even in castration-resistant setting, and hence may be targeted by second generation hormonal therapy. However, a subset of patients bears androgen-independent cancer biology with a short-term response to hormonal treatment, early and extensive visceral metastases, low PSA levels and poor outcomes.
Frank Z Pathol. Carcinoid Tumors.
Andreea ILIESIU – MÆDICA – a Journal of Clinical Medicine
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Ann N Y Acad Sci. Chromogranin A, neuron specific enolase, carcinoembryonic antigen, and hydroxyindole acetic acid evaluation in patients with neuroendocrine tumors.
Neuroendocrine cancer in breast.
CO; 8. Regul Pept. The poor prognosis factors in G2 neuroendocrine tumor. Rom J Morphol Embryol. The dedifferentiation of neuroendocrine tumor metastases: myth or reality? Octreotide for the treatment of hypoglycemia after insulin glargine overdose.
- Cancerul mamar nu e roz
- Revista Romana de Medicina de Laborator One of the major tools to evaluate this type of pathology is endocrine cancer review neuroendocrine markers as chromogranin A, serotonin, urinary 5-hydroxy indolacetic acid, and neuron specific enolase.
J Emerg Med. Biochemical testing for neuroendocrine tumors.
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The clinical relevance of chromogranin A as a biomarker for gastroenteropancreatic neuroendocrine tumors. Endocrinol Metab Clin North Am ;40 1 Well-differentiated neuroendocrine tumor and osteoporosis: incidental finding? Treatment of malignant midgut carcinoid tumours with a long-acting somatostatin analogue octreotide. Acta Oncol. Long-term clinical outcome of somatostatin analogues for gastric cancer globocan of pregressive, metastatic, well-differentiated entero-pancreatic endocrine carcinoma.
Ann Oncol. Predictive factors of efficacy of the somatostatin analogue octreotide as first neuroendocrine cancer aggressive therapy for advanced pancreatic endocrine carcinoma.